Wheatgrass Research

Isolation of a Vitamin E analog from a green barley leaf extract that stimulates release of prolactin and growth hormone from rat anterior pituitary cells in vitro.

Badamchian M, Spangelo B, Bao Y, Hagiwara Y, Hagiwara H, Ueyama H, Goldstein A. 1994. J. Nutr. Biochem. 5:145-150

We have previously reported that green barley leaf extract, a dried extract of young green barley leaves that is widely used in Japan and other countries as a nutritional supplement, contains a molecule(s) that enhances the release of growth hormone and/or prolactin from rat anterior pituitary cells in vitro. Using reverse-phase high performance liquid chromatography and fast atom bombardnent-mass spectrometry (FAB-MS) we have now isolated and chemically characterized the molecule possessing this neuroendocrine activity. The molecule is alpha-tocopherol succinate, an analog of alpha-tocopherol or vitamin E. This is the first report documenting a role for this vitamin E analog on pituitary endocrine release.

Dr. Chris Reynolds | Monday, April 25, 2011 | Comments (0) | Permalink

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